Three Studies Endeavour to Produce Potential HIV Vaccine
In a breakthrough achievement, scientists have tested the ability of certain proteins to produce antibodies. The three tests were conducted on rabbit, monkey and mice cells in the laboratory to ascertain capability of these antibodies to curb the detrimental effects of the human immunodeficiency virus (HIV) on human body.
Collaborative efforts of the scientists at The Scripps Research Institute (TSRI), International AIDS Vaccine Initiative (IAVI) and The Rockefeller University revealed the efficacy of an experimental vaccine to stimulate the immune system activity in mice that can halt the life threatening HIV infection.
Two of the researches published in the Journals Cell and Science were funded by the National Institute of Allergy and Infectious Diseases. Dennis Burton, chair of the department of immunology and microbial science, The Scripps Research Institute was involved in these two studies that used mouse models.
Burton informed that the results are pretty spectacular as the two studies have successfully tested a protein nanoparticle on two different mouse models that binds and activates cells needed to prevent HIV infection.
The third study published in Science and led by Weill Medical College of Cornell University tested the capability of a molecular complex to bind with cells in rabbit and monkey and to induce these animal cells to produce antibodies that can suffocate the HIV strain.
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